Ranitidine compared with cimetidine in the short-term healing of duodenal ulcer.

Cimetidine versus ranitidine in short term healing of duodenal ulcers.

Comparison of twice-daily ranitidine with standard cimetidine treatment of duodenal ulcer.

One hundred and three outpatients with endoscopically diagnosed duodenal ulcer were randomly allocated to treatment with either cimetidine 200 mg tds and 400 mg nocte, or ranitidine 150 mg bd for four weeks. The endoscopists were not aware of the treatment and took no part in the clinical management. On completion of treatment ulcers had healed in 43 of 51 (84%) patients given cimetidine and in...

Healing and relapse rates of duodenal ulcer with various H2 receptor antagonists.

Retrospective analysis of 119 endoscopically proven cases of duodenal ulcer, treated with Famotidin (40 mg),Cimetidine (800 mg) and Ranitidine (300 mg) at bed -time, showed heating rates of 91, 74 and 68%, respectively, at 6 weeks. Twenty patients were followed up for one year on maintenance dose and endoscoped at 3, 6 and 12 months. Despite taking the drug regularly a relapse rate of 14% was s...

Treatment of 'cimetidine-resistant' chronic duodenal ulcers with ranitidine or cimetidine: a randomised multicentre study.

Forty patients with endoscopically proven persistent duodenal ulcer who had been treated for six weeks with cimetidine (1 g/day) were randomly allocated to receive a further six weeks' treatment with cimetidine (1 g/day) or ranitidine (300 mg/day). Ulcers healed in 12 of 19 patients given cimetidine (63%) and in 13 of 21 given ranitidine (62%); two patients on cimetidine and two on ranitidine d...

Incompletely and completely healed duodenal ulcers' outcome in maintenance treatment: a double blind controlled study.

A six month, double blind, controlled study was performed in 107 asymptomatic duodenal ulcer patients who, after short term cimetidine treatment, showed complete or incomplete endoscopic healing. Patients were stratified according to the type of healing and randomly allocated to cimetidine (200 mg at lunch, 400 mg at bedtime) or placebo. Endoscopic examinations were carried out after six months...